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FAQ - Frequently asked questiones


What is FeNO?

FeNO stands for “fractional exhaled nitric oxide”, and is a standardized breath sample obtained from the bronchi. The NO that thus becomes measurable is used as a biomarker for the diagnosis and follow-up of bronchial asthma.

Why is FeNO measured?

Following an allergic reaction, the epithelial cells* in the lower respiratory tract produce increased amounts of NO. The nitric oxide or NO concentration in the exhaled breath therefore reflects the degree of allergic inflammation in the respiratory tract. The more severe the inflammation is, the more NO is produced and measured as FeNO.

*Epithelial cells lie together in single or multiple cell layers and cover all inner and outer surfaces of the human body.

What are the advantages of FeNO measurement?

FeNO measurement helps your doctor to diagnose allergic asthma. In addition, it is very likely that asthmatics with elevated FeNO levels will respond well to inhaled corticosteroids (ICS). [Dweik et al. 2011, Karrasch et al. 2017, Taylor et al. 2006] FeNO measurement can be used to monitor the progression of airway inflammation. Controlling asthma treatment by means of regular FeNO measurements can help to reduce the frequency of acute asthma episodes. [Petsky et al. 2016, Essat et al. 2016] A worsening of the inflammation is indicated by increased FeNO values, enabling your doctor to take therapeutic countermeasures at an early stage. [Bodini A et al. 2017]

When is FeNO measurement carried out?

FeNO measurement (inflammometry) is usually used to confirm a diagnosis of asthma in addition to the pulmonary function test. Regular FeNO measurements are also used for follow-up monitoring of asthma. The diagnostic value of FeNO testing for asthma diagnosis is comparable to the bronchoprovocation, or bronchial challenge test [Schneider et al. 2014].

How widespread and recognized is FeNO measurement?

The guidelines of the American Thoracic Society (ATS) recommend this method for diagnosis, therapy management, and monitoring of asthma patients. [ATS, Dweik et al. 2011] The British NICE Clinical Guideline on Asthma has recommended including FeNO measurement in the diagnosis algorithm in order to improve diagnostic quality, and considers the FeNO value to be an important parameter for long-term asthma management. FeNO measurement can also help to increase cost effectiveness. The German Guidelines for Diagnosis and Treatment of Asthma Patients also recommend using the FeNO value as an additional marker for confirming the asthma diagnosis.

What does ppb stand for?

NO concentration in the air is measured in ppb (parts per billion), i.e. a concentration of 10 ppb is equivalent to 10 nitric oxide molecules per billion air particles. (Factsheet of the Deutsche Atemwegsliga e.V.: FeNO measurement)

What does my FeNO result tell me?

FeNO threshold values depend, among other things, on height and gender; women have lower values than men, children lower values than adults. The guidelines of the American Thoracic Society (ATS) state that values between 0 and 25 ppb are low, between 25 and 50 ppb medium and above 50 ppb high. As a guide, values below 25 ppb can be considered normal (children below 20 ppb). Values above 50 ppb (children above 35 ppb) indicate active inflammation of the respiratory tract. In general, you and your doctor will determine your personal threshold value together. (Factsheet of the Deutsche Atemwegsliga e.V.: FeNO measurement)


Where can I buy Vivatmo me?

You can find a list of Vivatmo me dealers here:

Where can I reorder mouthpieces (oxycaps)?

You can find a list of Vivatmo oxycap dealers here:

Does Vivatmo me require regular maintenance or calibration?

Vivatmo me is calibrated by the manufacturer and due to the unique sensor technology, this calibration remains stable for the entire specified service life. The innovative measuring principle prevents the sensor from becoming depleted during the permissible number of measurements. Before each use, the device cleans the sensor surface of various impurities from the exhaled breath and thus optimally prepares it for the next measurement. This ensures you always get an accurate measuring result. There is therefore no need for you to recalibrate the device.

How do I perform FeNO measurement with Vivatmo me?

Instructions on how to use the Vivatmo me can be found here.

How should I clean and disinfect the handhelds?

Regularly wipe the device with a disinfection wipe that contains alcohol. Please note that the alcohol percentage should not exceed 30%. A higher percentage can cause damage to the display and remove labels. The following products have been verified for wipe disinfection by the manufacturer: mikrozid® universal wipes (Schülke).

Do the health insurance funds absorb the costs for FeNO measurement?

No. The costs for the Vivatmo me home monitoring device are not covered by the statutory health insurance funds. In some countries, FeNO measurement is reimbursed in the medical practice; in Germany, for example, by private health insurance companies.

How and where can I dispose of my Vivatmo at the end of its useful life?

Vivatmo can be disposed of after the end of its useful life at a recycling depot together with small electrical appliances. Vivatmo me must not be disposed of with household waste.

How are Oxycaps disposed of?

Oxycaps can be disposed of in household waste.

How often may I use the oxycap (mouthpiece)?

The oxycap is a complex system for processing breath samples and is not suitable for multiple use. After removal from the outer packaging, it can be used for 15 minutes. Thus, a maximum of five measurement attempts can be conducted until a valid value is obtained.

What is the Vivatmo app?

The Vivatmo app is a digital asthma diary. The Vivatmo app enables you to retrieve all important information relating to your asthma at a glance: FeNO values, symptoms, medication and pollen count. The FeNO results measured with the Vivatmo me device are transmitted to your smartphone via Bluetooth. The app automatically retrieves pollen data for your current location, keeping you constantly informed about possible triggers that can affect the course of the disease. You can also enter medication doses and personal wellbeing. Together with pollen and medication data, a monthly PDF report can be generated and printed or sent by e-mail for your records or to your physician. Regular reporting can help you and your doctor optimize your individual asthma therapy.

Where can I download the Vivatmo app?

The Vivatmo app is available from the Google Play Store as well as the App Store and can be downloaded for free.

Which operating system does the Vivatmo app run on?

The Vivatmo app is available for android in the Play Store and for iOS in the App Store.

What does the Vivatmo app cost?

The Vivatmo app is completely free. There are also no in-app costs incurred.

In which countries is the app available?

The Vivatmo app is available in almost every country in which Vivatmo me is available.

In which languages is the Vivatmo app available?

The Vivatmo app is available in German and English.

Why does the Vivatmo app need access to my location?

Pollen is a frequent symptom trigger for many asthma patients. By activating the location feature, you allow the app to retrieve the current pollen count for your region.

When is my position transmitted? Who can see it?

Your position is only transmitted if you open the app to check the current local pollen forecasts and is deleted immediately afterwards.